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. 2011 Mar 3;6(3):e17507. doi: 10.1371/journal.pone.0017507

Table 1. Prognostic clinicopathological variables as predictors for disease-specific survival in 249 non-GIST STSs (univariate analyses, log-rank test).

Characteristic Patients(n) Patients(%) Median survival(months) 5-Year survival(%) P
Age
≤ 20 years 20 8 15 40 0.126
21–60 years 113 45 68 52
>60 years 116 47 30 40
Gender
Male 110 44 41 46 0.390
Female 139 56 45 45
Patient nationality
Norwegian 167 67 63 51 0.011
Russian 82 33 22 34
Histological entity
Pleomorphic sarcoma 68 27 29 40 0.102
Leiomyosarcoma 67 27 45 46
Liposarcoma 34 14 NR 67
MF/MFT 20 8 43 50
Angiosarcoma 13 5 10 31
Rhabdomyosarcoma 16 6 17 38
MPNST 11 5 49 45
Synovial sarcoma 16 6 31 29
Other STSs 4 2 NR 18
Tumor localization
Extremities 89 36 100 53 0.348
Trunk 47 29 32 44
Retroperitoneum 37 25 25 38
Head/Neck 18 7 15 41
Visceral 58 23 30 42
Tumor size
≤ 5 cm 74 30 127 57 0.027
5–10 cm 91 37 44 45
>10 cm 81 32 28 36
Missing 3 1
Malignancy grade
1 61 25 NR 74 <0.001
2 98 39 41 45
3 90 36 16 26
Tumor depth
Superficial 17 7 NR 93 <0.001
Deep 232 93 36 42
Metastasis at time of diagnosis
No 206 83 76 53 <0.001
Yes 43 17 10 10
Surgery
Yes 228 92 59 50 <0.001
No 21 8 5 0
Resection margins
Free 178 71 127 66 <0.001
Not free/no surgery 71 29 10 18
Chemotherapy
No 191 77 52 47 0.424
Yes 58 23 29 40
Radiotherapy
No 176 71 48 46 0.590
Yes 73 29 38 43

Abbreviations: NR, not reached; MF/MFT, malignant fibroblastic/myofibroblastic tumors; MPNST, malignant peripheral nerve sheath tumor; NOS, not otherwise specified; non-GIST STS, non-gastro intestinal stromal tumor soft-tissue sarcoma.