Table II.
Interactions of MPD with the Protein
| MPD | Atom | Residue | Atom | Averaged distancea | Number of protomers in which the interaction was observed |
|---|---|---|---|---|---|
| MPD1 | CM | Asn176(A)b | Cγ | 4.12 | 18 |
| Asn176(A) | O | 4.09 | 20 | ||
| Asn176(A) | Nδ2 | 4.10 | 16 | ||
| Asn176(A) | Oδ1 | 4.10 | 16 | ||
| Gln177(A) | Nɛ2 | 4.42 | 10 | ||
| Trp179(A) | Cβ | 4.28 | 12 | ||
| Trp179(A) | Cδ1 | 4.26 | 14 | ||
| Trp179(A) | Cγ | 4.23 | 13 | ||
| Met197(A) | O | 4.29 | 10 | ||
| C1 | Trp179(A) | Cγ | 4.41 | 10 | |
| Gln194(A) | Oɛ1 | 3.83 | 19 | ||
| Arg200(A) | Cδ | 4.52 | 11 | ||
| Arg200(A) | Cγ | 4.33 | 11 | ||
| Arg200(A) | Cζ | 3.93 | 18 | ||
| Arg200(A) | Nɛ | 3.91 | 15 | ||
| Arg200(A) | Nη | 3.76 | 20 | ||
| O2 | Asn176(A) | Nδ2 | 4.06 | 15 | |
| Gln194(A) | Oɛ1 | 4.22 | 13 | ||
| Met197(A) | O | 3.45 | 25 | ||
| C2 | Met197(A) | O | 4.11 | 10 | |
| C3 | Gln177(A) | Nɛ2 | 4.40 | 10 | |
| Lys198(A) | O | 4.11 | 14 | ||
| O4 | Trp179(A) | Cδ1 | 4.27 | 11 | |
| Trp179(A) | Nɛ1 | 4.04 | 17 | ||
| C5 | Gln177(A) | Nɛ2 | 4.44 | 15 | |
| Lys198(A) | O | 3.80 | 17 | ||
| Thr199(A) | Cα | 4.51 | 10 | ||
| MPD2 | CM | Ser114(F) | O | 4.05 | 16 |
| His144(G) | O | 4.01 | 20 | ||
| C1 | Leu146(G) | Cβ | 4.36 | 11 | |
| Leu146(G) | Cδ2 | 4.25 | 13 | ||
| Asn178(A) | O | 4.29 | 18 | ||
| Gly180(A) | C | 4.12 | 18 | ||
| Gly180(A) | N | 4.12 | 18 | ||
| Gly180(A) | O | 3.14 | 24 | ||
| C2 | Gly180(A) | O | 3.75 | 25 | |
| O2 | Gly180(A) | O | 3.49 | 23 | |
| C3 | Ser114(F) | Cβ | 4.29 | 14 | |
| O4 | Asn178(A) | O | 4.14 | 17 | |
| C5 | Trp179(A) | Cα | 4.26 | 14 | |
| Trp179(A) | Cδ2 | 4.09 | 16 | ||
| Trp179(A) | Cɛ3 | 3.70 | 24 | ||
| Trp179(A) | Cζ3 | 4.17 | 15 | ||
| Gly180(A) | N | 4.38 | 12 |
a
Distances in all 28 protomers were averaged.
b
Letters in parentheses indicate the chain of the protomer when focusing on MPD mainly interacting with chain A.
Interactions within 4Å that were observed in more than 10 protomers are listed. The number of protomer in which the interaction was observed, and averaged distance in all 28 protomers are also shown. Interactions shown as bold are hydrogen bonds.