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Comparison of TGF-β isoforms biosynthesis
| Isoforms | Precursor ATGC Sequence |
Glycosylation Site |
Precursor Amino Acid |
Cysteine Residues |
Gene Location (chromosome) |
Gene Expression Site |
|---|---|---|---|---|---|---|
| TGFβ1 | GC Rich | 3 | 390 | 3 | 19q13 | Endothelial, connective tissue and hematopoietic cells |
| TGFβ2 | AT Rich | 3 | 442/414 | 6 | 1q41 | Epithelial and CNS Cells |
| TGFβ3 | Mix AT/GC | 4 | 410 | 5 | 14q24 | Mesenchymal Cells |
