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. 2011 Feb 21;11:14. doi: 10.1186/1472-6947-11-14

Table 3.

Dosing regions for several ampicillin indications

Indication Care area Age Weight (kg) Dose
Meningitis Bone marrow transplant ≤29 days < 8 100 mg/kg/dose IV q8h

≥8 100 mg/kg/dose IV q8 h up to a max single dose of 1 g

NICU, transitional care ≤7 days any 100 mg/kg/dose IV/IM q8 h (equivalent to 300 mg/kg/day)

≥8 any 75 mg/kg/dose IV q6 h (approx. 300 mg/kg/day)

PICU, cardiac ICU ≤29 days ≥8 100 mg/kg/dose IV q8 h up to a max single dose of 1 g

Any 100 mg/kg/dose IV q8h

Meningitis or osteomyelitis General care ≥14 yrs < 27 75 mg/kg/dose IV q6h

≥27 2 g IV q6h

Non-pediatric location ≤7 days ≥9 100 mg/kg/dose IV q8 h up to a max single dose of 1 g

< 9 100 mg/kg/dose IV q8h

8 days-14 yrs < 27 75 mg/kg/dose IV q6h

≥27 2 g IV q6h

14-18 yrs ≥27 & <45 2 g IV q6h

< 27 75 mg/kg/dose IV q6h

Pediatric liver transplant - post-op Any location - dosing region scenarios defined by order set use ≥0 days < 20 50 mg/kg q6 h × 4 doses

≥20 1 g q6 h × 4 doses

Pediatric liver transplant - pre-op Any location - dosing region scenarios defined by order set use ≥0 days < 20 50 mg/kg ONCALLPRN* to OR

≥20 1 g ONCALLPRN* to OR

*The dose is administered once a patient is called to the operating room.