Table 3.
Dosing regions for several ampicillin indications
Indication | Care area | Age | Weight (kg) | Dose |
---|---|---|---|---|
Meningitis | Bone marrow transplant | ≤29 days | < 8 | 100 mg/kg/dose IV q8h |
≥8 | 100 mg/kg/dose IV q8 h up to a max single dose of 1 g | |||
NICU, transitional care | ≤7 days | any | 100 mg/kg/dose IV/IM q8 h (equivalent to 300 mg/kg/day) | |
≥8 | any | 75 mg/kg/dose IV q6 h (approx. 300 mg/kg/day) | ||
PICU, cardiac ICU | ≤29 days | ≥8 | 100 mg/kg/dose IV q8 h up to a max single dose of 1 g | |
Any | 100 mg/kg/dose IV q8h | |||
Meningitis or osteomyelitis | General care | ≥14 yrs | < 27 | 75 mg/kg/dose IV q6h |
≥27 | 2 g IV q6h | |||
Non-pediatric location | ≤7 days | ≥9 | 100 mg/kg/dose IV q8 h up to a max single dose of 1 g | |
< 9 | 100 mg/kg/dose IV q8h | |||
8 days-14 yrs | < 27 | 75 mg/kg/dose IV q6h | ||
≥27 | 2 g IV q6h | |||
14-18 yrs | ≥27 & <45 | 2 g IV q6h | ||
< 27 | 75 mg/kg/dose IV q6h | |||
Pediatric liver transplant - post-op | Any location - dosing region scenarios defined by order set use | ≥0 days | < 20 | 50 mg/kg q6 h × 4 doses |
≥20 | 1 g q6 h × 4 doses | |||
Pediatric liver transplant - pre-op | Any location - dosing region scenarios defined by order set use | ≥0 days | < 20 | 50 mg/kg ONCALLPRN* to OR |
≥20 | 1 g ONCALLPRN* to OR |
*The dose is administered once a patient is called to the operating room.