Table 3.
Dosing regions for several ampicillin indications
| Indication | Care area | Age | Weight (kg) | Dose |
|---|---|---|---|---|
| Meningitis | Bone marrow transplant | ≤29 days | < 8 | 100 mg/kg/dose IV q8h |
| ≥8 | 100 mg/kg/dose IV q8 h up to a max single dose of 1 g | |||
| NICU, transitional care | ≤7 days | any | 100 mg/kg/dose IV/IM q8 h (equivalent to 300 mg/kg/day) | |
| ≥8 | any | 75 mg/kg/dose IV q6 h (approx. 300 mg/kg/day) | ||
| PICU, cardiac ICU | ≤29 days | ≥8 | 100 mg/kg/dose IV q8 h up to a max single dose of 1 g | |
| Any | 100 mg/kg/dose IV q8h | |||
| Meningitis or osteomyelitis | General care | ≥14 yrs | < 27 | 75 mg/kg/dose IV q6h |
| ≥27 | 2 g IV q6h | |||
| Non-pediatric location | ≤7 days | ≥9 | 100 mg/kg/dose IV q8 h up to a max single dose of 1 g | |
| < 9 | 100 mg/kg/dose IV q8h | |||
| 8 days-14 yrs | < 27 | 75 mg/kg/dose IV q6h | ||
| ≥27 | 2 g IV q6h | |||
| 14-18 yrs | ≥27 & <45 | 2 g IV q6h | ||
| < 27 | 75 mg/kg/dose IV q6h | |||
| Pediatric liver transplant - post-op | Any location - dosing region scenarios defined by order set use | ≥0 days | < 20 | 50 mg/kg q6 h × 4 doses |
| ≥20 | 1 g q6 h × 4 doses | |||
| Pediatric liver transplant - pre-op | Any location - dosing region scenarios defined by order set use | ≥0 days | < 20 | 50 mg/kg ONCALLPRN* to OR |
| ≥20 | 1 g ONCALLPRN* to OR | |||
*The dose is administered once a patient is called to the operating room.