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Study outcomes
| Outcome | Variable |
|---|---|
| Primary outcome | Smoke retention |
| • Tar (%) • Nicotine (%) |
|
| Secondary outcomes | Pulmonary function |
| • FEV1 reversibility (%) • FVC reversibility (%) |
|
| Smoking pattern | |
| • Mean inhalation time and volume (sec + ml) • Mean exhalation time and volume (sec + ml) • Total smoking time (min) • Amount of puffs (n) |
|
| Biomarkers | |
| • CRP and high sensitivity CRP (mg/l) • Fibrinogen (mg/l) |
