Table 5.
Monoclonal antibodies | ||||||||
---|---|---|---|---|---|---|---|---|
Virusesa | Clades | D101/1 (88b) |
A310/39 (145) |
64/1 (157) |
B9/5 (168) |
B59/5 (169) |
25/2 (205) |
|
NPAIVs | Dk/Pennsylvania/10218/84 (H5N2) | -c | + | + | + | + | + | + |
Swan/Hokkaido/4/96 (H5N3) | - | + | + | + | + | + | + | |
Swan/Hokkaido/51/96 (H5N3) | - | + | + | + | + | + | + | |
Swan/Hokkaido/67/96 (H5N3) | - | + | + | + | + | + | + | |
Dk/Hokkaido/447/00 (H5N3) | - | + | + | + | + | + | + | |
Dk/Hokkaido/69/00 (H5N3) | - | + | + | + | + | + | + | |
Dk/Mongolia/54/01 (H5N2) | - | + | + | + | + | + | + | |
Dk/Mongolia/500/01 (H5N3) | - | + | + | + | + | + | + | |
Dk/Mongolia/596/01 (H5N3) | - | + | + | + | + | + | + | |
Dk/Hokkaido/84/02 (H5N3) | - | + | + | + | + | + | + | |
Dk/Hokkaido/101/04 (H5N3) | - | + | + | + | + | + | + | |
Dk/Hokkaido/193/04 (H5N3) | - | + | + | + | + | + | + | |
Dk/Hokkaido/299/04 (H5N3) | - | + | + | + | + | + | + | |
Dk/Hokkaido/167/07 (H5N3) | - | + | + | + | + | + | + | |
Dk/Hokkaido/201/07 (H5N3) | - | + | + | + | + | + | + | |
Dk/Hokkaido/WZ21/08 (H5N2) | - | + | + | + | + | + | + | |
Dk/Hokkaido/WZ75/09 (H5N2) | - | + | + | + | + | + | + | |
Mal/Hokkaido/24/09 (H5N1) | - | + | + | + | + | + | + | |
HPAIVs | Ws/Mongolia/3/05 (H5N1) | 2.2 | + | - | + | + | - | + |
Ws/Hokkaido/1/08 (H5N1) | 2.3.2 | + | - | - | - | - | - | |
Pf/Hong Kong/810/09 (H5N1) | 2.3.4 | - | - | - | - | - | - |
The results, except Dk/Hokkaido/WZ21/08 (H5N2), Dk/Hokkaido/WZ75/09 (H5N2), Mal/Hokkaido/24/09 (H5N1), Ws/Hokkaido/1/08 (H5N1), and Pf/Hong Kong/810/09 (H5N1), were referred from previous report [20].
a Abbreviations: Dk (Duck), Mal (Mallard), Ws (Whooper swan), Pf (Peregrine falcon).
b Location of amino acid substitutions in antigenic variants selected in the presence of respective monoclonal antibodies [20].
c Dashes (-) indicate classical HA gene which is not classified into the clades 0 - 9.