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Effects of HO-1 on MMP-2 and MMP-9 expression in MCD diet-induced fibrosing steatohepatitis. mRNA expression of MMP-2 (A1) and MMP-9 (B1) were determined by real-time quantitative PCR; protein levels of MMP-2 (A2) and MMP-9 (B2) were detected by Western blot. Data are expressed as the mean ± SD (n = 6 per group). *P < 0.001, compared with the control group; #P < 0.05, ##P < 0.01, ###P < 0.001, compared with MCD group; $P < 0.01, $$P < 0.001, compared with MCD+Ad-GFP group.
