Table 2.
The response to amitriptyline: responses and doses of amitriptyline required and its benefit, treatment failures and side-effects
Male | Female | |
---|---|---|
Number of subjects | 17 | 45 |
% responding to amitriptyline with cessation of VCD | 94% | 82% |
Mean dose required (range) | 20 mg (10–40) | 20 mg (10–75) |
% with improved insomnia | 100% | 100% |
% with improved anxiety | 90% | 96% |
Treatment failures where VCD did not cease | 6% | 18% |
Intolerance due to side effects | Nil | 2 (dry mouth) |
Abbreviation: VCD, vocal cord dysfunction.