Table 1.

Allogeneic stem cell transplantation in patients with human immunodeficiency virus (HIV) between 1983 and 1999.

Reference	No. of patients	Graft	Conditioning regimen	Anti-retroviral therapy	Effect on HIV	Follow-up
Hasset et al. (1983) [12]	2	MUD	None	–	None	NR
Lane et al. (1984) [18]	1	SYN	None	–	CD4+ increased	Died after 12 months
Mitsuyasu et al. 1984 [19]	2	SYN	1 × VPL, TBI	–	None	Died day +41
Vilmer et al. (1987) [51]	1	SYN	NR	–	CD4+ increased	7 years
Verdonck et al. (1988) [14]	1	SYN	CPM, TBI	–	None	Died after 56 months
Holland et al. (1989) [24]	1	MUD	CPM, TBI	–	PCR negative from day +41, AB declined	Died on day +47
Saral & Holland (1994) [25]	7	4 × MUD 3 × SYN	6 × CPM and TBI 1 × CPM and BSN	–	1 patient* PCR-negative from days 40–120, 1–2 log decrease in virus titre	*Died later on GVHD 1 patient died < 30 days
Lane et al. (1990) [26]	16	SYN	None	–	None	10 alive (23·4 ± 4 months), 5 died (17·6 ± 5·5 months)
Furlini et al. (1988) [15]Bardini et al. (1991) [16]	1	MRD	CPM, TBI	–	None	Alive 3 years
Angelucci et al. (1991) [27]	1	MUD	BSN, CPM	–	None	Died on day +263
Aboulafia et al. (1991) [28]	1	SYN	ETP, BCNU, CPM	–	None	Died on day +52
Giri et al. (1992) [29]	1	MUD	CPM, ATG, TBI	–	None	Died after 13 months
Torlontano et al. (1992) [30]	1	MUD	BSN, CPM	–	Increased CD4/CD8 ratio	Died on day +48
Turner et al. (1992) [65]	1	SYN	CPM, TBI	AZT	p24 antigene negative	Died on day +18
Contu et al. (1993) [54]	1	MUD	BSN, CPM	AZT +IFN-α2	PCR negative from day +30, anti-HIV-AB negative after 4 months	Died on day +301
Campbell et al. (1999) [66]	1	SYN	CPM, BCNU, ETP	3TC, d4T	None	Alive 12 months

3TC, lamivudine; AB, antibodies; AZT, zidovudine; BCNU, carmustin; BSN, busulphan; CPM, cyclophosphamide; d4T, stavudine; ETP, etoposide; IFN-α2, interferon-alpha2; MRD, matched related donor; MUD, matched unrelated donor; NR, not reported; PCR, polymerase chain reaction; SYN, syngeneic donor; TBI, total body irradiation; VBL, vinblastine.