FIGURE 3.

C20-D₃-vitamin A reduces RPE autofluorescence in the Stargardt mouse. A, average retinaldehyde autofluorescence from RPE cells (eyecups), from 5 three-month-old mice administered vitamin A (control, left bar) and 5 three-month-old mice administered C20-D₃-vitamin A (treatment, right bar). Circles represent individual pixel intensity measurements for each flat mount image. Standard deviations are shown. ***: p < 0.001. B and C, representative confocal fluorescence microscopy images taken under identical conditions of an eyecup from a treated (C) and control animal (B).