FIGURE 6.

Guanine nucleotide-shifted residues highlighted in the Rv1739c STAS structure. A and C, STAS backbone representation is in blue; residues perturbed by ≥0.05 ppm following addition of 20 mm GTP (A) or GDP (C) are in red. B and D, the van der Waal surface representation of STAS structure (shown in two orientations) is in blue; residues were perturbed by ≥0.05 ppm following addition of 20 mm GTP (B) or GDP (D) are in red and annotated. Side chains of annotated residues Trp⁵⁰ and Thr⁶⁴ are in cyan.