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Effects of Klotho protein injection on renal cell density in UUO mice determined by MRI. A, typical ADC maps from mice before (Day 0) and after UUO (Day 3 and Day 7) administered with vehicle (upper panels) or Klotho (0.02 mg/kg, lower panels). B, changes in the average ADC values. Data indicate means ± S.E. *, p < 0.05 versus vehicle-treated mice at the same time points by two-tailed t test. #, p < 0.05 versus mice at Day 0 by two-tailed t test.
