General framework for using clinical decision support tools within the Veterans Health Administration electronic medical record (EMR) system to individualize care. The clinical decision support tool described in this report is only one example of a nearly infinite variety of ways in which the EMR may be used to adapt clinical strategies to the preferences, symptoms, behaviors, and clinical histories of individual patients (A). For example, a more comprehensive version of the clinical decision support tool described in this report could aim to improve medication adherence based on patient-level behavioral risk factors, symptoms, and comorbidities (B). EMR, electronic medical record; QA, quality assurance; ↑ increased; Hx, history.