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. 2011 Jan 15;10(2):268–277. doi: 10.4161/cc.10.2.14469

Figure 2.

Figure 2

Phenotypes of PB-PKC transgenic mice: PKCε overexpression leads to a preneoplastic phenotype. Homozygous males for PB-PKCα, PB-PKCδ, PB-PKCε and non-transgenic FVB control mice at 12 months old were analyzed. Histological analyses revealed significant epithelial hyperplasia and PIN lesions in both VP and DP from PB-PKCε mice. Representative H&E and HA stainings are shown. All microphotographs are 20x magnification.