Table 1.
Incidence of hyperplasia and PIN lesions in VP and DP of PB-PKC transgenic mice
Ventral prostate | Dorsal prostate | |||||
Mice | Age (months) | n | Hyperplasia, number (%) | PIN, number (%) | Hyperplasia, number (%) | PIN, number (%) |
Wild-type | 12 | 14 | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
PB-PKCα | 12 | 8 | 1 (12%)* | 0 (0%) | 1 (12%)* | 0 (0%) |
PB-PKCδ | 12 | 6 | 1 (8%) | 0 (0%) | 0 (0%) | 0 (0%) |
PB-PKCε | 8 | 7 | 7 (100%) | 6 (86%) | 6 (86%) | 5 (71%) |
PB-PKCε | 12 | 17 | 17 (100%) | 17 (100%) | 17 (100%) | 17 (100%) |
PB-PKCε | 14 | 4 | 4 (100%) | 4 (100%) | 4 (100%) | 4 (100%) |
PB-PKCε | 16 | 3 | 3 (100%) | 3 (100%) | 3 (100%) | 3 (100%) |
Mild hyperplasia.