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. Author manuscript; available in PMC: 2011 Mar 4.
Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2010 Mar 5;153B(2):397–408. doi: 10.1002/ajmg.b.30992

Table 3.

Log-Logistic Survival Model Estimates Fitting 2-Year Predictions from the Langbehn et al. and Gutierrez & MacDonald Models to Huntington’s Disease Onset From the PREDICT-HD Data.

Ideal Calibration Langbehn et al. Gutierrez & MacDonald
Coefficient S.E. Coefficient S.E.
Intercept 0.693a 0.278 0.223 0.5656 0.208
Logit of 2-year onset probability – −0.704 0.101 −0.826 0.124
Log (Scale coefficient) _ −0.781 0.109 −0.777 0.109
Logit(2-year probability)/Scale −1.000 −1.537 0.198 −1.796 0.207
a

log(2) ≈ 0.693.

Note: Inter- rater frailty was highly statistically significant for both models: Chi-square = 52.9, 24.1 df for Langbehn et al and chi square = 51.8, df = 24.1 for Gutierrez and MacDonald. p < .0001 in both cases.