Table 1.
Microarray results of transcripts showing greater than 5-fold difference in expression between WKY and LEW, in basal macrophages, with <1% false discovery rate (FDR). Data are sorted according to fold change
| Affymetrix transcript identity |
Gene name | Gene Symbol | QTL position |
p-value (LEW vs. WKY basal) |
Fold- Change (LEW vs. WKY basal) |
|---|---|---|---|---|---|
| 7113955 | Fc receptor, IgG, low affinity III, related sequence | Fcgr3-rs | Crgn1 | 2.30E-07 | 52.4 |
| 7028278 | Leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3-like |
Lilrb3l | 6.91E-09 | 36.7 | |
| 7332712 | Matrix metallopeptidase 7 | Mmp7 | 4.34E-06 | 12.1 | |
| 7216236 | Olfactory receptor 1684 | Olr1684 | 1.64E-07 | 12.0 | |
| 7047485 | Paired-Ig-like receptor B | Pirb | 3.49E-09 | 11.6 | |
| 7332774 | Transient receptor potential cation channel, subfamily C, member 6 | Trpc6 | 4.35E-05 | 11.2 | |
| 7317031 | Nephroblastoma overexpressed gene | Nov | 4.46E-09 | 10.2 | |
| 7367852 | Rattus norvegicus cDNA clone IMAGE:5598800 5-, mRNA sequence | IMAGE:5598800 | 1.97E-05 | 7.9 | |
| 7147913 | Ligase IV, DNA, ATP-dependent | Lig4 | 2.31E-07 | 6.0 | |
| 7080736 | Chemokine (C-C motif) ligand 9 | Ccl9 | 1.04E-05 | 5.4 | |
| 7294643 | Pleckstrin homology domain containing, family H (with MyTH4 domain) member 2 | Plekhh2 | 3.56E-06 | −5.0 | |
| 7037483 | HtrA serine peptidase 1 | Htra1 | 3.28E-06 | −5.7 | |
| 7270146 | Immunoreceptor Ly49si2 | Ly49si2 | 3.14E-06 | −5.8 | |
| 7334400 | Rho GTPase-activating protein | Grit/Rics | 1.39E-07 | −6.8 | |
| 7025757 | Arginase 1, liver | Arg1 | 1.54E-05 | −6.9 | |
| 7080663 | Schlafen 8 | Slfn8 | 4.64E-06 | −8.3 | |
| 7374731 | Carbonic anhydrase VB, mitochondrial | Ca5b | 1.30E-07 | −10.0 | |
| 7081895 | Insulin-like growth factor 2 mRNA binding protein 1 | Igf2bp1 | 1.81E-08 | −11.3 | |
| 7270138 | Immunoreceptor Ly49si1 | Ly49si1 | 5.04E-08 | −12.8 |
p-value - uncorrected ANOVA p-value; Fold-change - positive values show genes down-regulated in WKY, while negative values show genes up-regulated in WKY compared to LEW macrophages