Table 3. Parameter estimates under site pair models for the MADS and MEF2s coding regions.

Model	ω	Parameter estimates	PSS		2Δ
Model 0(one-ratio)	0.012	ω = 0.077	none	−1693.329	29.568**
Model 3(discrete)	0.024	p: 0.467 0.425 0.109	none	−1678.545
		ω: 0.001 0.015 0.156
Model 1a	0.019	p: 0.989 0.011	not allowed	−1689.428	0
(NearlyNeutral)		ω: 0.008 1.000
Model 2a	0.019	p: 0.989 0.011 0.000	none	−1689.428
(PositiveSelection)		ω: 0.008 1.000 7.394
		(note that p[2] is zero)
Model 7(beta)	0.015	p = 0.160 q = 9.200	not allowed	−1674.351	0
Model 8(beta&ω)	0.015	p0 = 0.999 p = 0.160 q = 9.200	none	−1674.352
		(p1 = 0.00001) ω = 1.899
		(note that p1 is nearly zero)

Note: The ω represents for K_a/K_s that is the average of selection across all sites in the MEF2 coding regions. PSS represents the number of sites under positive selection.

**Significance with .