Table 3.
Early stage ovarian or fallopian tube cancers identified in BRCA mutation carriers
| Case # | Age at dx | BRCA1/2 Mutation | Grade | Dominant Mass | Histology | Bilateral or Unilateral? | Primary size | Stage |
|---|---|---|---|---|---|---|---|---|
| 7 | 32 | BRCA1 | high | ovary | serous carcinoma | bilateral | 12 × 6 × 6 cm | IB |
| 8 | 43 | BRCA1 | high | ovary | serous carcinoma | unknown | unknown | IIA |
| 9 | 56 | BRCA1 | high | ovary | serous carcinoma | bilateral | 11 cm | IC |
| 10 | 55 | BRCA1 | high | ovary | serous carcinoma | unilateral | 8 cm | IIC |
| 11 | 54 | BRCA1 | high | ovary | undifferentiated carcinoma | unilateral | unknown | IA |
| 12 | 50 | BRCA1 | high | fallopian tube | poorly differentiated carcinoma | unilateral | 2 cm | IA |
| 13 | 40 | BRCA1 | high | fallopian tube | serous carcinoma | unilateral | 8 × 5 × 3 cm | II |
| 14 | 50 | BRCA1 | high | fallopian tube | serous carcinoma | unilateral | 2 × 1 × 1 cm | IA |
| 15 | 54 | BRCA2 | high | ovary | poorly differentiated carcinoma | unilateral | 7 × 7 × 5 cm | IIB |
| 16 | 59 | BRCA2 | high | ovary | serous carcinoma | bilateral | 7 cm | IIC |
| 17 | 55 | BRCA2 | high | ovary | serous carcinoma | bilateral | 14 × 7 × 6 cm | IB |
| 18 | 50 | BRCA2 | high | ovary | serous carcinoma | bilateral | 7 × 5 × 3 cm | IIA |
| 19 | 61 | BRCA2 | high | ovary | serous carcinoma | unilateral | 15 cm | IIA |
| 20 | 41 | BRCA1 and BRCA2 | high | ovary | serous carcinoma involving left ovary and detached fragments in RFT lumen | unilateral | 6 cm | IIB |
RFT, right fallopian tube.