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. Author manuscript; available in PMC: 2012 Mar 31.
Published in final edited form as: Neuroscience. 2011 Jan 22;178:82–88. doi: 10.1016/j.neuroscience.2011.01.031

Figure 2.

Figure 2

Age-related reduction in orexin neurons. A. Representative labeling of OxA-IR neurons (black cell bodies indicated by arrows) in the LH/PFA of a young rat. B. Representative labeling of OxA-IR cells in the LH/PFA of an aged rat. Note the sparser distribution of orexin neurons in both lateral and medial to the fornix (Fx). C. Aging was associated with a significant reduction of OxA-IR neurons in both medial and lateral sectors of the LH/PFA, as well as overall. *P < 0.05; **P < 0.01. Scale bars = approximately 100 μm for both A and B.