. Author manuscript; available in PMC: 2012 Mar 1.

Published in final edited form as: Clin Cancer Res. 2011 Jan 13;17(5):1082–1089. doi: 10.1158/1078-0432.CCR-10-2560

Table 4. Multivariable Cox Proportional Hazards Models.

Recurrence-Free Survival Estimates

	Hazard Ratio	95% Confidence Interval	P-value
Mutation Status
Wild Type	1.0
Mutant	0.17	(0.041, 0.72)	0.016
Pathological Stage
I and II	1.0
III	5.32	(2.55, 11.10)	<0.0001
Nuclear Grade
2	1.0
3	1.25	(0.16, 9.65)	0.830
Overall Survival

	Hazard Ratio	95% Confidence Interval	P-value

Mutation Status
Wild Type	1.0
Mutant	0.45	(0.16, 1.29)	0.138
Pathological Stage
I and II	1.0
III	4.44	(2.16, 9.12)	<0.0001
Nuclear Grade
2	1.0
3	0.63	(0.14, 2.85)	0.550