Table 4.

Gene Expression in Normal dogs, Untreated Heart failure Control Dogs and Heart failure Dogs Treated with Chronic Carotid Sinus Baroreflex (CSB) Activation

	Normal (n=6)	Control (n=6)	CSB Activation (n=8)
GADPH (du)	0.34 ± 0.02	0.35 ± 0.03	0.36 ± 0.02
β1-Adrenergic Receptor (du)	0.55 ± 0.06	0.26 ± 0.04*	0.51 ± 0.08†
β2-Adrenergic Receptor (du)	0.23 ± 0.03	0.26 ± 0.04	0.25 ± 0.03
β-Adrenergic Receptor Kinase (du)	0.27 ± 0.05	1.22 ± 0.08*	0.54 ± 0.06*†
Adenylyl Cyclase (du)	0.64 ± 0.05	0.34 ±0.04*	0.53 ± 0.06*†
Angiotensinogen (du)	0.36 ± 0.05	0.74 ± 0.06*	0.39 ± 0.03†
eNOS (du)	0.71 ± 0.07	0.44 ± 0.07*	0.56 ± 0.07*†
iNOS (du)	0.34 ± 0.06	0.72 ± 0.06*	0.43 ± 0.05*†

GADPH = glyceraldehyde-3-phosphate dehydrogenase ; eNOS = endothelial nitric oxide synthase. iNOS – inducible nitric oxide synthase ;

^*=p<0.05 vs. Normal,

^†=p<0.05 vs. Control.