Table 2.
Clinical and pathologic features of the study population
| Variable | Value | % |
|---|---|---|
| Age (years) | 65 (29–85) | |
| Gender (male/female) | 243/191 | 56/44 |
| Pre-operative serum concentration | ||
| CEA (ng/ml) | 2.3 (0–36 000) | |
| CA19.9 (U/ml) | 57.1 (0.2–27 000) | |
| Type of resection | ||
| Extended hepatectomy | 84 | 19.4 |
| Major hepatectomy | 220 | 50.7 |
| Minor hepatectomy | 130 | 29.9 |
| Lymph node dissection | ||
| None | 121 | 27.9 |
| Sampling | 43 | 9.9 |
| Standard | 157 | 36.2 |
| Extended | 113 | 26.0 |
| Additional abdominal procedures | 134 | 30.9 |
| Macroscopic type classification | ||
| Mass forming | 390 | 89.9 |
| Periductal infiltrating or mixed mass forming + periductal | 39 | 9.0 |
| Intraductal | 5 | 1.1 |
| Tumour size (cm) | 60 (10–250) | |
| Tumour number | ||
| Single | 293 | 67.5 |
| Multiple | 140 | 32.3 |
| NA | 1 | 0.2 |
| Tumour grade | ||
| Well/moderately differentiated | 259 | 59.7 |
| Poorly or undifferentiated | 147 | 33.9 |
| NA | 28 | 6.4 |
| Presence of vascular invasion | ||
| Present | 211 | 48.6 |
| Absent | 187 | 43.1 |
| NA | 36 | 8.3 |
| Presence of perineural invasion | ||
| Present | 163 | 37.5 |
| Absent | 183 | 42.2 |
| NA | 88 | 20.3 |
| Lymph node status | ||
| pNx | 121 | 27.9 |
| pN0 | 193 | 44.5 |
| pN1 | 113 | 26.0 |
| NA | 7 | 1.6 |
| Distant metastases | 14 | 3.2 |
Continuous variable are reported as median (range); NA, not available.