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. 2011 Feb 14;8:69. doi: 10.1186/1743-422X-8-69

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Copyright ©2011 Liang et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Ex vivo IFN-γ ELISPOT responses to HBV S and C open reading frame peptide pools and recombinant HBV proteins. (A) Comparison of subjects with HBsAg seroclearance, immunotolerant HBV carriers and inactive HBsAg carriers. Each line represents the mean number of spot-forming cells induced by each stimulus. Each dotted line represents the cut-off value for a positive test in the ELISPOT assay. (B) Comparison of the frequency of positive responses obtained in HBsAg seroclearance and control populations. (C) Comparison of the mean number of spots/well from the subjects with positive tests in each group. Each bar represents the mean ± SD.