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. 2011 Feb 14;8:69. doi: 10.1186/1743-422X-8-69

Figure 2.

Figure 2

Results of the intracellular cytokine staining assay for interferon gamma. (A) Individual responses of CD8+ T cells stimulated by HBV peptide pools in subjects with HBsAg seroclearance (Group1), immunotolerant HBV carriers (Group2) and inactive HBsAg carriers (Group3). (B) Individual responses of CD4+ T cells stimulated by HBV peptide pools in subjects with HBsAg seroclearance, immunotolerant HBV carriers and inactive HBsAg carriers. (C) The mean frequencies of positive CD4+ and CD8+ T cell responses in the three populations. (D) Comparison of mean frequencies of IFN-g+ secreting CD8+ and CD4+ T cells in subjects with positive responses to either of the peptide mixtures in the three groups. Each dotted line in 2A and 2B represents the cut-off value for a positive test. Each bar in 2D represents the mean ± SD percentage of IFN-g secreting CD4+ and CD8+ cells in subjects with positive responses to either the C or S peptide pools.