Brain regions in which local volume was significantly associated with (a) Extraversion, (b) Conscientiousness, (c) Neuroticism, and (d) Agreeableness, as hypothesized (see also Table 1). Coordinates indicate the locations of the brain slices. Color is related to effect size, with lighter color signifying a larger effect, and darker color signifying a smaller effect. PFC = prefrontal cortex.