Table 1.

Brain Regions in Which Relative Local Volume Was Associated With a Big Five Trait

Trait and brain region	Brodmann's area	Centroid (Talairach coordinates): x, y, z	Number of voxels	β
Extraversion
Medial orbitofrontal cortex	11	5, 33, –20	646*	0.35
Superior temporal sulcus	22	–60, –32, 4	57	–0.27
Cerebellum	—	10, –74, –6	256	–0.29
Neuroticism
Medial temporal lobe, basal ganglia	28/34	–12, –12, –7	1,822*	–0.41
Medial frontal gyrus	8/9	3, 38, 39	1,582*	–0.37
Mid-cingulate gyrus	24	15, –4, 31	693*	0.31
Mid-cingulate gyrus, caudate	24	–20, –1, 25	995*	0.34
Middle temporal gyrus	37	–52, –56, 2	654*	0.36
Precentral gyrus	4	56, –10, 26	320*	–0.32
Cerebellum	—	22, –37, –42	697*	0.39
Cerebellum	—	–52, –46, –30	25	0.29
Cerebellum	—	3, –74, –8	124	0.28
Agreeableness
Superior temporal sulcus	22/42	52, –20, 3	533*	–0.34
Posterior cingulate	29	–5, –45, 6	813*	0.34
Fusiform gyrus	18	36, –81, –7	1,059*	0.37
Middle temporal gyrus	21/37	–60, –54, 8	17	0.26
Precentral gyrus	6	55, –9, 31	105	–0.28
Precuneus	7	–2, –54, 43	144	–0.28
Middle frontal gyrus	8/9	–45, 25, 39	229	–0.30
Cerebellum	—	–6, –79, –13	64	0.26
Conscientiousness
Middle frontal gyrus	8/9/10	–35, 36, 32	629*	0.43
Inferior frontal gyrus	44	–54, 16, 12	35	–0.27
Paracentral lobule	5	–3, –34, 48	22	–0.27
Fusiform gyrus	19	35, –80, –11	476*	–0.32
Superior parietal lobule	7	34, –60, 48	222	0.31
Openness/Intellect
Inferior parietal lobule	40	47, –31, 43	188	0.31
Lingual gyrus	18	27, –78, –3	40	–0.28
Middle temporal gyrus	37	–60, –46, –10	19	–0.28

Note: N = 116.

^*p < .05, corrected for cluster size.