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Addition of dexamethasone (DEX) synergistically increases TCDD-dependent induction of luciferase activity in the CALUX cell bioassay. H4L1.1c4, H1L1.1c2 and G16L1.1c8 cells were incubated with 1 nM TCDD, 10 μM DEX or TCDD plus DEX for 4 h as indicated. Luciferase activity was determined as described. Luciferase values are expressed as the percentage of that induced by 1 nM TCDD and represent the mean ± SD of triplicate determinations.
