Table 5.
Analogues based on virtual screening via docking
| Compd | R1 | R2 | Ring | n | IC50 (μM) | Kd (μM) | Activation of Viral Infectivity |
|---|---|---|---|---|---|---|---|
| 38 | Cl | F |  |
5 | 68.3 ± 9.6 | 3.1 | 0.0 |
| 39 | Cl | F |  |
1 | 50.4 ± 14.2 | 1.2 | 0.6 |
| 40 | Cl | F |  |
1 | >100 | N.D. | 0.0 |
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