Fig. 8.

Expression of pro-lymphangiogenic factors is elevated in the skin of PU.1^–/– mice. Semi-quantitative RT-PCR was used to determine the relative level of gene expression in PU.1^–/– (n=4) compared with wild-type (n=4) E16.5 skin samples. Data are depicted as the percentage change in mRNA expression in PU.1^–/– compared with wild-type skin and represent the mean ± s.e.m. No change in expression between PU.1^–/– and wild-type skin is represented by 0%. P-values were calculated using Student's paired t-test. ^*, P≤0.05.