Table 1.
Disease | Inclusion | Abnormal protein |
---|---|---|
Alzheimer disease | Extracellular neuritic plaque | Aβ peptide |
Cytosolic neurofibrillatory tangles | Tau | |
Parkinson disease | Lewy bodies | α-synuclein |
Familial amyotrophic lateral sclerosis | Intracellular inclusions | SOD1 |
Huntington disease | Nuclear, cytosolic inclusion | Huntingtin |
Spinocerebellar ataxia 1, 2, 3 | Nuclear inclusions | Ataxin 1, 2, 3 |
Spinobulbar muscular atrophy | Nuclear inclusions | Androgen receptors |