Table 2.
Disease | Neurons affected | Hsc70 levels | Frequency |
---|---|---|---|
Alzheimer disease | entorhinal cortex and hippocampus | Low | High |
Parkinson disease | dopaminergic neurones in the substantia nigra pars compacta | Intermediate | Intermediate |
Amyotrophic lateral sclerosis | motor neurons of the spinal cord and motor cortex | High | Low |