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. 2011 Jan 21;20(7):1438–1455. doi: 10.1093/hmg/ddr024

Figure 6.

Figure 6.

(A) Mitochondrial-encoded protein COX1 expression in frontal cortex sections from grade III (B) and grade IV (C) HD patients and controls (A). Uniform immunoreactivity of COX1 was found in brain sections from control subjects (D). Interrupted immunoreactivity of COX1 was found in brain sections from grade III (E) and grade IV (F) HD patients. Arrows indicate immunoreactivity. Images were photographed at ×40 (upper panel) and ×100 (bottom panel). (B) Quantitative analysis of COX1. Significantly decreased cytochrome b in grade III (P< 0.001) and grade IV (P< 0.0001) HD patients. Error bars indicate mean ± SEM.