Table 1.

mRNA fold changes of mitochondrial fission/fusion and matrix genes in frontal cortex brain specimens from grade III and grade IV HD patients

HD brains—pathology stage	Drp1	Fis1	Mfn1	Mfn2	Opa1	CypD	TOMM40
HD3 patient 1	10.9	7.79	−4	−3.44	−4.34	9.91	1.14
HD3 patient 2	3.62	6.86	−2.5	−4.7	−2.63	31.19	1.25
HD3 patient 3	2.8	13.75	−2.85	−50	−2.85	24.5	−1.07
Mean fold change in HD3 patients	5.8	9.5	−3.1	−19.4	−3.3	21.9	1.1
HD4 patient 1	5.96	36.18	−2	−33.3	−1.61	26.6	2.67
HD4 patient 2	7.04	32.38	−2.85	−50	−1.61	20.71	5.8
HD4 patient 3	4.35	30.75	−2.5	−4.34	−1.58	51.5	2.53
Mean fold change in HD4 patients	5.8	33.1	−2.45	−29.2	−1.6	32.9	3.7