Table 2. Density of blood vessels in different brain areas after traumatic brain injury (TBI).
|
Blood vessel density (hit points per mm2) |
|||
|---|---|---|---|
| Control (n=6) | 6 hours after TBI (n=6) | 2 weeks after TBI (n=7) | |
| Cortex | |||
| Perilesional cortex | 426±13 | 399±10 | 477±18## |
| Contralateral cortex | 402±14 | 387±9 | 446±16 |
| Hippocampus (total) | |||
| Ipsilateral | 221±9 | 222±8 | 222±3 |
| Contralateral | 213±8 | 221±2 | 209±5 |
| CA1 stratum oriens | |||
| Ipsilateral | 233±7 | 201±5** | 225±7# |
| Contralateral | 244±8 | 238±9 | 231±5 |
| Thalamus | |||
| Ipsilateral | 368±22 | 412±16 | 431±31 |
| Contralateral | 357±25 | 384±9 | 381±15 |
The number of rats is in parentheses. Data are shown as mean±s.e.m. Vessel densities in the perilesional cortex and ipsilateral CA1 stratum oriens were significantly between the control group, 6-hours group, and 2-week group (P<0.05, Kruskal–Wallis test). Post hoc statistical significances are shown: **P<0.01 as compared with controls (Mann–Whitney U-test); #P<0.05, ##P<0.01 as compared with the 6-hour time point (Mann–Whitney U-Test). Control measures from each time point did not vary; thus, control data were pooled.