Table 2. Pre-diagnostic socio-demographic and health status risk factors for cancer-related PTSS and severe PTSSa.
3 Months post surgery
|
15 Months post surgery
|
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---|---|---|---|---|---|---|---|---|---|---|---|---|
PTSS | Severe PTSS |
Severe PTSS age adjusted
|
PTSS | Severe PTSS |
Severe PTSS age adjusted
|
Severe PTSS 3 months adjusted
b
|
||||||
N | Mean (s.d.) | (%) | OR | (95% CI) | N | Mean (s.d.) | (%) | OR | (95% CI) | OR | (95 % CI) | |
Age | P=0.71 | P<0.001 | P<0.001c | P<0.001 | P=0.20 | P=0.20c | P=0.07 | |||||
26–35 years | 95 | 17.05 (11.03) | 6.3 | 1.00 | (Referent) | 73 | 17.36 (12.77) | 12.3 | 1.00 | (Referent) | 1.00 | (Referent) |
36–49 years | 900 | 19.76 (14.77) | 17.2 | 3.09 | 1.33–7.18 | 773 | 17.39 (14.31) | 12.9 | 1.06 | 0.51–2.19 | 0.57 | 0.26–1.26 |
50–59 years | 1282 | 20.38 (16.17) | 20.5 | 3.83 | 1.66–8.85 | 1126 | 16.68 (15.95) | 16.0 | 1.35 | 0.66–2.77 | 0.69 | 0.32–1.49 |
60–69 years | 1041 | 20.35 (16.69) | 23.2 | 4.49 | 1.94–10.40 | 940 | 14.58 (15.47) | 13.4 | 1.10 | 0.53–2.27 | 0.48 | 0.22–1.06 |
Marital status | P=0.47 | P=0.15 | P=0.44 | P=0.04 | P=0.33 | P=0.32 | P=0.17 | |||||
Married or cohabiting | 2537 | 19.90 (15.77) | 19.4 | 1.00 | (Referent) | 2236 | 16.29 (15.35) | 14.3 | 1.00 | (Referent) | 1.00 | (Referent) |
Divorced, separated or married – single | 408 | 21.14 (15.97) | 22.5 | 1.21 | 0.94–1.55 | 354 | 17.29 (15.70) | 16.7 | 1.20 | 0.89–1.63 | 1.12 | 0.78–1.62 |
Widow – single | 179 | 20.87 (16.78) | 25.1 | 1.16 | 0.81–1.67 | 158 | 13.66 (14.90) | 11.4 | 0.75 | 0.45–1.26 | 0.54 | 0.30–0.99 |
Unmarried – single | 188 | 20.05 (15.79) | 19.7 | 1.11 | 0.76–1.62 | 159 | 15.28 (14.67) | 11.9 | 0.83 | 0.50–1.36 | 0.81 | 0.46–1.45 |
Children | P=0.16 | P=0.007 | P=0.01 | P=0.25 | P=0.08 | P=0.08 | P=0.53 | |||||
No | 384 | 18.70 (14.53) | 14.8 | 1.00 | (Referent) | 326 | 15.02 (14.48) | 11.0 | 1.00 | (Referent) | 1.00 | (Referent) |
Yes | 2934 | 20.29 (16.01) | 20.8 | 1.45 | 1.08–1.95 | 2586 | 16.36 (15.44) | 14.7 | 1.38 | 0.96–1.98 | 1.15 | 0.75–1.75 |
Education (ISCED 97 based) | P=0.01 | P<0.001 | P<0.001 | P=0.26 | P<0.001 | P<0.001 | P=0.03 | |||||
Lower secondary general (7 years) | 539 | 22.42 (18.18) | 27.8 | 1.00 | (Referent) | 466 | 16.55 (17.23) | 18.0 | 1.00 | (Referent) | 1.00 | (Referent) |
Lower secondary general (8–10 years) | 466 | 20.71 (16.65) | 22.1 | 0.84 | 0.62–1.14 | 404 | 17.64 (16.29) | 15.8 | 0.83 | 0.57–1.20 | 0.97 | 0.63–1.50 |
Upper secondary (11–13 years) | 1317 | 20.41 (15.79) | 20.3 | 0.74 | 0.58–0.95 | 1142 | 16.54 (15.47) | 16.1 | 0.85 | 0.63–1.14 | 1.19 | 0.84–1.69 |
Tertiary < master degree (14–17 years) | 797 | 18.29 (14.12) | 15.2 | 0.53 | 0.40–0.71 | 718 | 14.97 (13.43) | 9.2 | 0.44 | 0.31–0.64 | 0.68 | 0.45–1.03 |
Tertiary master degree (⩾18 years) | 160 | 17.42 (12.24) | 10.6 | 0.36 | 0.21–0.62 | 147 | 15.11 (13.43) | 8.2 | 0.39 | 0.20–0.74 | 0.77 | 0.38–1.56 |
Social status (ISCO-88 based) | P<0.001 | P<0.001 | P<0.001 | P=0.01 | P<0.001 | P<0.001 | P=0.38 | |||||
Top manager or employee – upper level | 381 | 16.72 (12.55) | 11.5 | 1.00 | (Referent) | 338 | 14.92 (12.78) | 8.6 | 1.00 | (Referent) | 1.00 | (Referent) |
Employee – medium level | 559 | 18.92 (14.60) | 16.1 | 1.48 | 1.01–2.19 | 502 | 15.61 (13.88) | 11.2 | 1.32 | 0.83–2.12 | 1.02 | 0.60–1.74 |
Employee – basic level | 820 | 19.64 (15.32) | 17.3 | 1.61 | 1.12–2.31 | 704 | 16.17 (15.09) | 13.6 | 1.67 | 1.08–2.59 | 1.21 | 0.74–1.97 |
Employee – others or in education | 333 | 20.63 (16.84) | 22.2 | 2.16 | 1.44–3.25 | 288 | 17.78 (16.29) | 18.8 | 2.49 | 1.54–4.03 | 1.56 | 0.89–2.72 |
Self-employed or assisting spouse | 124 | 20.42 (15.88) | 20.2 | 1.88 | 1.10–3.24 | 111 | 14.67 (14.30) | 12.6 | 1.58 | 0.80–3.12 | 0.89 | 0.40–2.00 |
Unemployed, recipient of temporary allowance, cash or pre-retirement benefits, and so on | 619 | 20.95 (16.50) | 23.4 | 2.18 | 1.49–3.20 | 556 | 15.44 (15.84) | 14.9 | 2.03 | 1.27–3.23 | 1.12 | 0.68–1.86 |
Old age pension | 169 | 21.61 (17.83) | 27.2 | 2.52 | 1.52–4.16 | 155 | 14.82 (15.44) | 14.8 | 2.16 | 1.15–4.07 | 0.86 | 0.43–1.71 |
Recipients of early retirement pension, rehabilitation, or sickness benefits | 306 | 24.60 (18.31) | 32.4 | 3.48 | 2.32–5.20 | 252 | 20.55 (18.79) | 23.4 | 3.47 | 2.12–5.66 | 1.53 | 0.87–2.68 |
Personal income | P=0.003 | P<0.001 | P<0.001 | P=0.007 | P<0.001 | P<0.001 | P=0.04 | |||||
⩽20 000 $ | 499 | 22.35 (17.53) | 28.1 | 1.00 | (Referent) | 436 | 18.67 (17.67) | 20.0 | 1.00 | (Referent) | 1.00 | (Referent) |
>20 000 $ and ⩽30 000 $ | 618 | 21.22 (17.31) | 23.9 | 0.83 | 0.63–1.08 | 544 | 15.06 (15.85) | 14.7 | 0.68 | 0.49–0.96 | 0.68 | 0.45–1.04 |
>30 000 $ and ⩽40 000 $ | 688 | 20.94 (16.14) | 21.9 | 0.78 | 0.59–1.03 | 600 | 17.11 (15.59) | 17.7 | 0.82 | 0.59–1.13 | 1.04 | 0.71–1.54 |
>40 000 $ and ⩽55 000 $ | 879 | 18.68 (14.60) | 15.4 | 0.51 | 0.39–0.68 | 775 | 15.29 (13.95) | 10.3 | 0.43 | 0.31–0.61 | 0.64 | 0.43–0.95 |
>55 000 $ | 627 | 18.33 (13.88) | 14.5 | 0.48 | 0.35–0.65 | 551 | 15.65 (14.05) | 11.1 | 0.47 | 0.33–0.68 | 0.76 | 0.50–1.16 |
Household net wealth (per person) | P=0.15 | P=0.39 | P=0.03 | P<0.001 | P=0.001 | P<0.001 | P=0.02 | |||||
<0 $ | 677 | 20.99 (16.41) | 21.6 | 1.00 | (Referent) | 571 | 18.37 (15.97) | 18.4 | 1.00 | (Referent) | 1.00 | (Referent) |
⩾0 $ and <20 000 $ | 598 | 20.38 (15.52) | 20.9 | 0.87 | 0.66–1.15 | 533 | 17.20 (15.82) | 14.3 | 0.71 | 0.51–0.98 | 0.73 | 0.50–1.08 |
⩾20 000 $ and <55 000 $ | 626 | 19.79 (15.95) | 18.8 | 0.76 | 0.58–1.00 | 557 | 15.09 (14.94) | 14.5 | 0.72 | 0.52–0.99 | 0.81 | 0.55–1.19 |
⩾55 000 $ and <120 000 $ | 736 | 20.54 (15.98) | 21.1 | 0.82 | 0.63–1.07 | 645 | 16.19 (15.68) | 14.6 | 0.71 | 0.52–0.97 | 0.77 | 0.53–1.11 |
⩾120 000 $ | 674 | 18.84 (15.32) | 18.0 | 0.64 | 0.48–0.85 | 600 | 14.28 (13.85) | 9.7 | 0.43 | 0.30–0.62 | 0.50 | 0.33–0.75 |
Urbanicity (municipality size) | P=0.86 | P=0.95 | P=0.92 | P=0.94 | P=0.45 | P=0.47 | P=0.59 | |||||
<10 000 | 564 | 20.67 (16.22) | 20.9 | 1.00 | (Referent) | 491 | 16.84 (15.92) | 14.3 | 1.00 | (Referent) | 1.00 | (Referent) |
10 000–50 000 | 1201 | 20.10 (15.92) | 20.1 | 0.92 | 0.72–1.18 | 1065 | 16.23 (15.62) | 15.2 | 1.08 | 0.79–1.46 | 1.19 | 0.82–1.72 |
50 000–300 000 | 719 | 20.06 (15.93) | 20.4 | 0.95 | 0.72–1.25 | 621 | 16.29 (15.49) | 14.5 | 1.02 | 0.73–1.43 | 1.09 | 0.73–1.64 |
Copenhagen – suburbs | 521 | 20.15 (15.58) | 19.2 | 0.87 | 0.65–1.18 | 459 | 16.05 (14.66) | 13.9 | 0.97 | 0.67–1.40 | 1.23 | 0.79–1.91 |
Copenhagen – center | 307 | 19.20 (15.25) | 19.2 | 0.91 | 0.64–1.29 | 271 | 15.14 (13.97) | 10.7 | 0.72 | 0.46–1.14 | 0.84 | 0.49–1.44 |
Ethnicity | P=0.41 | P=0.66 | P=0.61 | P=0.63 | P=0.93 | P=0.93 | P=0.84 | |||||
Not immigrant or descendant | 3211 | 20.10 (15.91) | 20.0 | 1.00 | (Referent) | 2821 | 16.20 (15.34) | 14.3 | 1.00 | (Referent) | 1.00 | (Referent) |
Immigrant or descendant | 101 | 20.55 (14.01) | 21.8 | 1.13 | 0.70–1.84 | 86 | 16.83 (15.49) | 14.0 | 0.97 | 0.52–1.81 | 1.07 | 0.54–2.15 |
Psychiatric history | P<0.001 | P<0.001 | P<0.001 | P=0.002 | P<0.001 | P<0.001 | P=0.008 | |||||
No | 3090 | 19.72 (15.67) | 19.1 | 1.00 | (Referent) | 2728 | 15.92 (15.11) | 13.5 | 1.00 | (Referent) | 1.00 | (Referent) |
Yes | 228 | 25.38 (17.29) | 32.9 | 2.10 | 1.57–2.81 | 184 | 20.45 (17.94) | 26.1 | 2.28 | 1.61–3.22 | 1.78 | 1.16–2.72 |
CCI | P=0.002 | P<0.001 | P=0.001 | P=0.03 | P=0.001 | P=0.002 | P=0.26 | |||||
No comorbidity | 2955 | 19.78 (15.63) | 19.2 | 1.00 | (Referent) | 2604 | 16.06 (15.27) | 13.9 | 1.00 | (Referent) | 1.00 | (Referent) |
CCI score =1 | 296 | 22.27 (16.71) | 26.0 | 1.38 | 1.05–1.83 | 251 | 16.66 (15.22) | 14.7 | 1.07 | 0.74–1.55 | 0.84 | 0.55–1.31 |
CCI score >1 | 58 | 27.07 (19.81) | 37.9 | 2.26 | 1.32–3.90 | 49 | 22.86 (18.24) | 32.7 | 3.01 | 1.63–5.55 | 1.80 | 0.80–4.06 |
Abbreviations: CCI=Charlson comorbidity index; CI=confidence interval; IES=impact of events scale; ISCED=International Standard Classification of Education; ISCO-88= International Standard Classification of Occupation; OR=odds ratio; PTSS=post-traumatic stress symptom.
PTSS=IES; severe PTSS=IES total score ⩾35.
Adjusted for PTSS scores and severe PTSS measured at 3 months post surgery.
Unadjusted.
Age- and baseline-adjusted ORs in bold differs significantly (95% CI) from the reference group (OR=1.00). Missing observations are not shown. As a consequence totals (N) differs slightly.