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. 2011 Jan 25;104(4):664–672. doi: 10.1038/sj.bjc.6606062

Figure 1.

Figure 1

(A) Extracellular signal-regulated protein kinase 5 expression in PC3–ERK5 stable clone (left-hand panel) and parental PC3 cells (right-hand panel) following siRNA-mediated ERK5 directed knockdown (KD), compared with non-silencing control (NS) and sham transfection (Nil). (B) Proliferation assay following ERK5 KD in PC3–ERK5 cells. (C) Effects of a range of doses of PD184352 (MEK inhibitor) on proliferation of PC3 cells.