Table 2. Prostate histopathology of Gamitrinib–G4-treated TRAMP mice (group 2; 19.7 weeks).
| Mouse no. | Neuroendocrine (%) | Adenocarcinoma (%) | PIN (%) | Inflammation (Score) |
|---|---|---|---|---|
| 2999 | 0 | 1 (DLP) | 99 (DLP); 20 (VP); 10 (AP) | +1 (VP) |
| 4255 | 0 | 0 | 95 (DLP); 95 (VP); 10 (AP) | +2 (VP) |
| 4260 | 0 | 0 | 100 (DLP); 50 (VP) | +1 (VP) |
| 4464 | 0 | 0 | 95 (DLP); 95 (VP); 25 (AP) | 0 |
| 4473 | 0 | 0 | 100 (DLP); 50 (VP); 10 (AP) | 0 |
Abbreviations: AP=anterior prostate; DLP=dorso-lateral prostate; Gamitrinib=GA mitochondrial matrix inhibitor; PIN=prostatic intraepithelial neoplasia; TRAMP=Transgenic Adenocarcinoma of the Mouse Prostate; VP=ventral prostate.