Table 1.
Main characteristics of selected studies
First author | Year | Ethnicity | Cases | Controls | Case | Control | Pathological parameters of cases | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
Gly/Gly | Gly/Arg | Arg/Arg | Gly/Gly | Gly/Arg | Arg/Arg | ||||||
Wang | 2004 | Caucasian | 284 | 97 | 125 | 117 | 42 | 53 | 40 | 4 | Stratified by Gleason score (7-9 vs. 5-6), pathological stage (T3 vs. T2), lymph node metastasis (positive vs. negative), and PSA recurrence (positive vs. negative) |
Wang | 2004 | African American | 45 | 94 | 37 | 6 | 2 | 76 | 18 | 0 | |
FitzGerald | 2009 | Caucasian | 1254 | 1251 | 587 | 544 | 123 | 631 | 496 | 124 | Stratified by Gleason score [≥7(4+3) vs.≤7(3+4)], and pathological stage (regional/distant vs. local) |
FitzGerald | 2009 | African American | 146 | 80 | 104 | 39 | 3 | 60 | 18 | 2 | |
Ho | 2009 | Caucasian | 397 | 439 | 183 | 182 | 32 | 235 | 167 | 37 | - |
Ma | 2008 | Asian | 492 | 344 | 163 | 196 | 133 | 125 | 152 | 67 | Stratified by tumor stage (stage D vs. A+B+C) a, and Gleason score (8-10 vs. 2-7) |
a Stage A (T1a-bN0M0), StageB (T1c-2N0M0), Stage C (T3-4N0M0) and Stage D (T1-4N1M0-1 orT1-4N0-1M1) by the modified Whitmore-Jewett system.