Skip to main content
. 2011 Mar 7;6(3):e16601. doi: 10.1371/journal.pone.0016601

Figure 6. Immunohistochemical staining of albumin in the brains of Naglu mice.

Figure 6

Albumin immunostaining can clearly be seen within the blood vessels (A, B, C, green, arrowheads) of control C57 BL/6J mouse at 12 months of age. In Naglu mice, albumin extravasation (green, arrows) can be seen in various brain structures (D, E, F) at early (3 months of age), (G, H, I) at late (6 months of age), and (J, K, L) end stages of disease (10 months of age). Cx – cerebral cortex, Hip – hippocampus, Crb – cerebellum. Scale bar in A through L is 25 µm.