. Author manuscript; available in PMC: 2012 Mar 1.

Published in final edited form as: J Biol Inorg Chem. 2010 Nov 18;16(3):373–380. doi: 10.1007/s00775-010-0733-z

Table 1.

Summary of kinetic and biological data

Compound	k_obs × 10⁴ ± SD (s⁻¹)^a	a × 100 ± SD (%)	t_1/2 (min)	IC_50,H460 (μM)	IC_50,HL-60 (μM)
1	1.4 ± 0.37	29 ± 3	83 ± 22	0.35^b	2.8^b
2	5.7 ± 0.58	68 ± 2	21 ± 2	0.028^b	3.0^b
3	2.1 ± 0.40	41 ± 3	55 ± 10	0.078^c	3.9^c
4	1.1 ± 0.40	28 ± 5	104 ± 38	6.1^d	10.6^d

Data were obtained through cell proliferation assays. IC₅₀ is the concentration required to inhibit cell proliferation by 50% SD standard deviation

At 37 °C, pH 7.5

See [22]

See [25]

See [24]