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. Author manuscript; available in PMC: 2011 Mar 8.
Published in final edited form as: J Allergy Clin Immunol. 2008 Jan 7;121(4):976–982. doi: 10.1016/j.jaci.2007.11.014

FIG 3.

FIG 3

Impaired TCR-induced IκB degradation in patient T cells. Highly enriched maternal (left) and patient (right) CD3+ T cells were control-treated or activated for 30 minutes with C305 anti-TCR mAb and whole cell lysates evaluated for the presence of IκB (top) or actin (bottom) by Western blot. Numbers depict band intensity relative to control, and blots are representative of 2 experiments.