Scheme 2.
(a) Pd(PPh3)Cl2, CuI, DMF/Et3N, N2 protection; (b) NaOH, toluene, reflux, 16 h; (c) Na2S2O4, NH3·H2O, THF/H2O (v/v 1:1 ), rt; (d) NiCl2·6H2O/NaBH4, THF/MeOH (v/v 1:1 ).
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