Table 1.
Clinical characteristics of normal and IUGR study groups
| Normal (n = 27) | IUGR (n = 14) | P value | |
|---|---|---|---|
| Maternal data | |||
| Age (yr) | 32.0 (21–41) | 31.5 (24–44) | NS |
| Smokers | 3/27 (11) | 4/14 (28) | NS |
| Nulliparous | 3/27 (11) | 5/14 (36) | NS |
| Fetal data | |||
| Males | 9/27 (33) | 5/14 (36) | NS |
| Gestational age (wk) | 39 (37–40) | 38 (35–40) | 0.0006 |
| Birth weight (g) | 3320 (2320–4400) | 2400 (1565–2960) | <0.0001 |
| Placenta weight (g) | 640 (509–883) | 464 (313–700) | 0.0012 |
| Customized birth weight percentile | 53 (23–99) | 2 (0–27) | <0.0001 |
| Abnormal umbilical artery Doppler flow | 0/27 (0) | 3/14 (21) | 0.0341 |
| Oligohydramnios | 0/27 (0) | 8/14 (57) | <0.0001 |
Values represent ratio (%) or median (range). In the IUGR group, 1) one neonate was diagnosed with Prader-Willi syndrome at 8 months of age; 2) one woman was epileptic and was treated with a low dose of lamotrigine (100 mg twice daily); and 3) another woman was a heroin addict who had been taking reducing doses of methadone during pregnancy. NS, Not statistically significant.