. 2010 Jul 21;95(10):4748–4755. doi: 10.1210/jc.2010-0473

Table 2.

Association of IL-6 and CRP with survival among Rancho Bernardo Study participants

			Women
	Men		Estrogen use		No estrogen use
	Time ratio (95% CI)	P value	Time ratio (95% CI)	P value	Time ratio (95% CI)	P value
IL-6 per sd^a
Unadjusted	0.82 (0.79, 0.86)	<0.001	0.93 (0.86, 1.01)	0.07	0.85 (0.80, 0.89)	<0.001
Age adjusted	0.85 (0.81, 0.88)	<0.001	0.95 (0.87, 1.03)	0.21	0.90 (0.86, 0.94)	<0.001
+Body size/LS/comorbidities^b	0.85 (0.81, 0.89)	<0.001	0.97 (0.89, 1.06)	0.49	0.90 (0.86, 0.95)	<0.001
+Lipids/blood pressure^c	0.85 (0.81, 0.89)	<0.001	0.98 (0.90, 1.06)	0.56	0.92 (0.87, 0.96)	<0.001
+CRP	0.87 (0.83, 0.92)	<0.001	0.97 (0.89, 1.06)	0.54	0.92 (0.87, 0.97)	0.003
CRP per sd^a
Unadjusted	0.85 (0.8, 0.89)	<0.001	0.95 (0.86, 1.06)	0.37	0.97 (0.92, 1.03)	0.29
Age adjusted	0.86 (0.82, 0.91)	<0.001	0.97 (0.88, 1.06)	0.46	0.96 (0.91, 1.01)	0.14
+Body size/LS/comorbidities^b	0.89 (0.84, 0.93)	<0.001	0.98 (0.89, 1.09)	0.76	0.96 (0.92, 1.02)	0.17
+Lipids/blood pressure^c	0.88 (0.84, 0.93)	<0.001	0.99 (0.89, 1.11)	0.91	0.91 (0.93, 1.03)	0.47
+IL-6	0.91 (0.86, 0.97)	0.003	1.01 (0.89, 1.14)	0.90	1.01 (0.96, 1.07)	0.63

CI, Confidence interval; LS, lifestyle.

The sd values are 2.6 pg/ml for IL-6 and 2.6 mg/liter for CRP in men and 2.5 pg/ml for IL-6 and 2.9 mg/liter for CRP in women.

Models include age, body mass index, waist circumference, daily alcohol use, current smoking, diabetes, CVD, hypertension, cancer, estimated GFR, and total number of medications.

Models include previous model variables plus systolic blood pressure, diastolic blood pressure, HDL cholesterol, LDL cholesterol, and triglycerides.