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A, Study design, showing simultaneous suppression of endogenous testosterone secretion (GnRH = GnRH agonist, leuprolide) and weekly injection of testosterone enanthate for 20 wk. B, Testosterone suppresses hepcidin dose-dependently in men. Log-transformed serum hepcidin levels (ng/ml) are shown at various sampling points in the 20-wk testosterone treatment study.
