Figure 4.

Ethanol intake (grams per kilogram and its corresponding percentage, upper and lower sections, respectively) in male and female adolescent rats during Phases 1 and 4 of the ethanol intake protocol as a function of day of assessment (sessions 1, 2, 3, and 4) and ethanol treatment during initiation. Initiation occurred on PD28 and consisted of a single administration of ethanol (2.5 g/kg, i.g.) or its vehicle (0.0 g/kg, tap water). Then, during PD37–52, the adolescents were subjected to a procedure for the assessment of ethanol consumption, which consisted of four phases. The graph depicts ethanol intake during Phases 1 and 4. Each of these phases was composed of four sessions, in which animals had access to water and a given ethanol solution (3, 4, 5, or 6% ethanol, for sessions 1, 2, 3, and 4, respectively). Data were collapsed across sex. The sex factor did not exert a significant main effect or significantly interact with the remaining variables. The smaller bar graphs depict ethanol intake during Phases 1 and 4, averaged across sessions. The vertical bars indicate SEM.