Table 3.
Summary of the receiver operating characteristic analysis during the early recovery duration
85–90 mins | 115–130 mins | 145–160 mins | 175–190 mins | 205–220 mins | 235–250 mins | |
---|---|---|---|---|---|---|
AUC | ||||||
PSA | 0.85 | 0.82 | 0.80 | 0.93 | 0.70 | 0.70 |
N10-P15 | 0.67 | 0.73 | 0.75 | 0.85 | 0.68 | 0.72 |
p Value | ||||||
PSA | .0006 | .019 | .023 | .0001 | .17 | .16 |
N10-P15 | .26 | .13 | .06 | .001 | .22 | .16 |
Sensitivity | ||||||
PSA | 0.78 | 0.78 | 0.78 | 0.78 | 0.78 | 0.67 |
N10-P15 | 0.44 | 0.89 | 0.67 | 0.89 | 0.56 | 1.00 |
Specificity | ||||||
PSA | 0.83 | 0.83 | 0.83 | 1.00 | 0.67 | 0.83 |
N10-P15 | 1.00 | 0.67 | 0.83 | 0.83 | 0.83 | 0.50 |
ThOptimal (%) | ||||||
PSA | 8.06 | 5.86 | 8.51 | 11.29 | 9.3 | 13.99 |
N10-P15 | 13.3 | 0.0 | 10.4 | 11.9 | 21.0 | 0.0 |
AUC, Area under the receiver operating characteristic curve; PSA, phase space area. The AUC was used to evaluate the overall accuracy of the test. A p value of <.05 (italicized) indicates that the AUC is significantly different from 0.5, indicating that the quantitative marker has the ability to distinguish between the two outcome groups. Sensitivity was defined as the proportion of rats with good functional outcome classified correctly and specificity was defined as the proportion of rats with poor functional outcomes classified correctly using PSA as the classification criterion. ThOptimal gives the value of the marker (as a percentage of baseline) for best separation between the groups, i.e., lowest false-positive and false-negative rates. Receiver operating characteristic parameters derived using N10-P15 peak-to-peak amplitudes are indicated below the values derived using the PSA marker.