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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Curr Opin Chem Biol. 2010 Jul 31;14(6):721–727. doi: 10.1016/j.cbpa.2010.07.002

Figure 3.

Figure 3

Structures of trapoxen, a naturally occurring HDAC inhibitor, and K-trap, a trapoxen derivative tethered to a solid support. The latter was a key reagent in the identification of HDACs as the target of trapoxen.