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. Author manuscript; available in PMC: 2012 Feb 25.
Published in final edited form as: Chem Biol. 2011 Feb 25;18(2):252–263. doi: 10.1016/j.chembiol.2010.12.008

Figure 2. Purification, identification and synthesis of heterotaxin (1).

Figure 2

A) GC trace of the regioisomers in the active pool. B) Active regioisomer (1) after separation (see Supplemental Experimental Procedures), phenotypic assay, and structural assignment. C) Regioselective synthetic route towards gram quantities of heterotaxin (1) and analogs (27–31).